Thoughtful solvent selection enables companies to reduce the environmental impact of their products and processes, support safer workplace settings, and provide their customers a safer user experience. The first steps required in selecting a suitable alternative for a problematic solvent involves information gathering. The information found in Gaylord’s Solvent Replacement site is intended to provide starting information to those interested in finding a safer solvent for their products and processes. In addition to this information, Gaylord offers consultation to assist companies seeking to work with DMSO.
Please contact us for any formulation support needs, we’re happy to help.
Powerful and Safe
| Solvent Class | Solvent | CAS# | mp,°C | bp,°C | Water Solubility g/100g H20 @ 25°C | Evaporation Rate (BuOAc=1) | VOC | Flammability Flash Point, °C (CC) | Legislative Restrictions |
|---|---|---|---|---|---|---|---|---|---|
| Alcohol | n-butanol | 71-36-3 | -89.8 | 117 | 9 | 0.46 | 100% | 29 | |
| Isopropyl Alcohol (IPA) | 67-63-0 | -89.5 | 82.3 | Miscible | 1.7 | 100% | 12 | ||
| Ethanol | 64-17-5 | -114.1 | 78.2 | Miscible | 1.7 | 100% | 13 | ||
| Methanol | 67-56-1 | -98 | 64.7 | Miscible | 2.9 | 100% | 11 | ||
| Aliphatic Hydrocarbon | Mineral Spirits | 8052-41-3 | -58 | 149-213 | Insoluble | 0.13 | 100% | 40 | |
| Hexane | 110-54-3 | -95 | 69 | Insoluble | 8.3 | 100% | |||
| Aromatic Hydrocarbon | AR-150 | 64742-94-5 | N/A | 179 | Negligible | 0.07 | 100% | 66 | |
| Toluene | 108-88-3 | -95 | 111 | 0.07 | 2.24 | 100% | 4 | ||
| Benzene | 71-43-2 | 5.5 | 80.1 | 1.88 | 3.5 | 100% | -11.63 | ||
| Carboxylic Acid | Formic Acid | 64-18-6 | 8.3 | 101 | Miscible | 2.1 | 100% | 50 | |
| Acetic Acid | 64-19-7 | 16.7 | 118 | Miscible | 0.97 | 100% | 40 | ||
| Dipolar Aprotic | Dimethyl Sulfoxide | 67-68-4 | 18.55 | 189 | Miscible | 0.026 | 100% | 89 | |
| N, N - Dimethyl Acetamide (DMAC) | 129-19-5 | -20 | 165 | Miscible | 0.2 | 100% | 63 | ||
| N-Methyl pyrrolidone (NMP) | 9872-50-4 | -24 | 202 | 100 | 0.03 | 806-1026 g/L | 86 | REACH banned1 | |
| Acetonitrile (ACN) | 75-05-8 | -46 | 81 | Miscible | 5.8 | 100% | 6 | ||
| N, N - Dimethyl Formamide (DMF) | 68-12-2 | -61 | 153 | Miscible | 0.17 | 100% | 58 | ||
| Nitromethane | 75-52-5 | -28.7 | 101.2 | 111 | 1.3 | 100% | 36 | ||
| Ester | Propylene Carbonate | 108-32-7 | -49 | 241 | 25 | 0.005 | Exempt | 132 | |
| Ethyl Acetate (ETAC) | 141-78-6 | -84 | 77 | 10 | 4.1 | 100% | -3 | ||
| Methyl Soyate | 67784-80-9 | >200 | Insoluble | <1 | 4% | >94 | |||
| Ether | Tetrahydrofuran (THF) | 109-99-9 | -108 | 66 | Miscible | 8 | 100% | -17 | |
| 1,3 Dioxolane | 646-06-0 | -95 | 75 | Miscible | 3.5 | 100% | -3 | ||
| 1,4-Dioxane | 12-91-1 | 11.8 | 101 | Miscible | 2.7 | 100% | 12 | ||
| Diethyl Ether | 60-29-7 | -116 | 34.6 | 8 | 11.8 | 100% | -40 | ||
| Butyl Cellusolve (Carbitol) | 111-90-0 | -76 | 202 | Miscible | 0.01 | 91 | |||
| Halogenated Hydrocarbon | Dichloromethane | 75-09-2 | -97 | 40 | 2 | 27.5 | Exempt | ||
| Parachlorobenzotrifluoride (PCBTF) | 98-56-6 | -36 | 138 | Insoluble | 0.9 | Exempt | 43 | ||
| Chloroform | 67-66-3 | -63.5 | 61.2 | 7.95 | 11.6 | 100% | |||
| Ketone | Acetone | 67-64-1 | -95 | 56 | Miscible | 6.3 | Exempt | -17 | |
| Methyl Isobutyl Ketone (MIBK) | 108-10-1 | -84 | 117 | 2 | 1.6 | 100% | 14 | ||
| Water | 7732-18-5 | 0 | 100 | - | 0.3 | None |