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Procipient® (Dimethyl Sulfoxide USP, PHEUR)

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Solve your Topical and Parenteral challenges with Procipient® (Dimethyl Sulfoxide USP, PHEUR). Gaylord Chemical’s Procipient® is the only grade of DMSO suitable for healthcare and drug delivery applications. Procipient is manufactured under GMP conditions following ICH Q7 guidelines, conforming to both the USP and Ph. Eur. monographs. It is supported by several regulatory dossiers making it the only DMSO product with this level of regulatory support. 

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AgXalt™

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AgXalt™ X-100 is the first in a line of next generation agrichemical formulation solvents designed with performance, safety, and environmental impact at its core. AgXalt™ X-100 has global regulatory clearances and unique solvent properties that make it a powerful tool for the agrichemical formulator’s toolbox.

 

 

 

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Dimethyl Sulfoxide (DMSO)

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Dimethyl Sulfoxide (DMSO) is a powerful, safe, and highly versatile polar aprotic solvent used across a wide range of industries and applications. From uses in agriculture and microelectronics to aerospace, DMSO improves product performance and process efficiency while reducing EH&S impact. Gaylord Chemical is the sole DMSO producer in The Americas and a leading DMSO supplier globally.

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Dimethyl Sulfide (DMS)

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 Dimethyl Sulfide (DMS) is a low molecular weight sulfur compound which is primarily used in olefin processing (ethylene furnace passivation) and fine chemical synthesis. Given its low toxicity and unique odor profile, it also has uses in flavor and fragrance formulation. Gaylord Chemical is the leading supplier of DMS globally.

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Our markets include:

Agriculture

AgXalt™ is the first in a line of next generation formulation solvents designed to helps producers, formulators, and farmers safely and effectively apply critical resources to farmland. As a highly polar, water-soluble, super solvent AgXalt™ enhances solubility for hard to dissolve active ingredients across a diverse range of formulation types.

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Biotechnology

Dimethyl sulfoxide (DMSO) has various functions in the Biotechnology segment. It is the most widely used medium for the cryopreservation of living cells and tissue and is regularly utilized in the synthesis and purification of proteins and peptides. Similar to its role in some small molecule pharmaceuticals, DMSO is highly effective in drug delivery systems designed to deliver proteins, peptides or carbohydrates.

Gaylord Chemical’s Procipient® is the only DMSO manufactured under cGMP conditions following ICH Q7 guidelines, conforming to both the USP and Ph. Eur. Monographs and is the most recommended DMSO for biotechnology applications.  

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Flavor and Fragrance

Dimethyl sulfide (DMS) is utilized as a small but critical component in perfumery to enhance certain attractive qualities of various fragrances. DMS is also used as a component in flavorings for dairy products and for enhancing corn-related flavors. It is listed in the US Food Chemical Codex and the Code of Federal Regulations as a synthetic flavoring substance and adjuvant (CFR 21 §172.515).

Gaylord’s DMS FNF grade is the DMS of choice for flavors and fragrance producers around the world given its extremely high purity and easy to use packaging.

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Industrial Cleaning

Dimethyl Sulfoxide (DMSO) is used broadly across a number of households, industrial, and institutional cleaning applications from paint stripping to polyurethane and chemical reactor cleaning. It is the ideal formulation solvent for applications where a safe yet powerful solvent is required. 

Gaylord is a leading producer of DMSO and well equipped to support industrial cleaning customer’s supply and product development needs.

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Polymer Processing

Dimethyl sulfoxide (DMSO) is a powerful solvent capable of dissolving highly insoluble monomers and retaining high molecular weight polymers in solution, which makes it the ideal solvent for a number of applications involving polymers. The unique solvent properties of DMSO are critical to its use in the synthesis of chemically resistant polymers and engineering resins such as carbon fiber, polysulfones, ultrafiltration membranes, and polymer dispersions. 

Gaylord is a leading producer of DMSO and well equipped to support material processing customer requirements, both large and small. 

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Microelectronics

Dimethyl Sulfoxide (DMSO) is utilized in the microelectronics industry as an essential component in photoresist stripping products used to manufacture semiconductor devices and TFT-LCD displays. 

Gaylord’s DMSO EL-10 Grade is consistently produced with extremely low metals content and very high purity with this highly sensitive end-use in mind. 

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Olefin Processing

Dimethyl Sulfide (DMS) is utilized in a number of olefin processing steps to ensure the efficient and safe handling of O&G fractions. Gaylord Chemical has remained the leading supplier of Dimethyl Sulfide (DMS) to the US gulf coast ethylene industry for decades. 

With continuous on-purpose DMS Exact-S® production since 1962, industry-leading product purity specifications, and a dedicated fleet of DMS tank wagons, Gaylord’s DMS business was built to be the most reliable DMS provider in the industry.

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Pharmaceuticals

Dimethyl Sulfoxide (DMSO) is widely used in the pharmaceutical industry for applications in drug discovery, API synthesis, and analytical laboratory testing. DMSO is also approved for use as an excipient solvent in pharmaceutical drugs and is itself an active pharmaceutical ingredient.

Gaylord Chemical’s Procipient® is the only DMSO manufactured under cGMP conditions following ICH Q7 guidelines, conforming to both the USP and Ph. Eur. Monographs and is only suitable DMSO for pharmaceutical applications.

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Performance Chemicals

Dimethyl Sulfoxide (DMSO) is a versatile dipolar aprotic solvent that offers distinct advantages in the synthesis of specific compound classes. It plays an important role as both a reactant and a reaction solvent in these chemical products.

Dimethyl Sulfide (DMS) also plays a role in synthesis, both as a solvent and as a reducing agent. Alkylated derivatives of DMS are useful epoxidation reagents. Many organic reactions utilize a borane-Dimethyl Sulfide complex.

Gaylord’s DMS and DMSO are produced to the highest purity specifications in the industry which is key to ensuring synthesis

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Solvent Replacement

Achieving the right balance between performance and safety is critical in the area of chemical formulation. It can be a challenge to find solvents that are safe, yet powerful enough to dissolve difficult components and form stable formulations. As a dipolar aprotic solvent, DMSO is recognized as being a superior solvent and has been referred to as the “super solvent.” A defining characteristic of this powerful solvent which distinguishes it from other dipolar aprotic solvents is its safety and toxicology profile. In many cases, DMSO is less toxic than other solvents and is often used as the safe, yet effective alternative to more problematic solvents. While a superior solvent on its own, DMSO may need to be blended with other ingredients to mimic the solvency properties of other chemicals.

Gaylord’s mission is to assist formulators in replacing problematic solvents with comparable DMSO blends which are both safe and effective. 

Locate one of our Distributors or contact us to reach a member of our technical support team for assistance with your company’s reformulation efforts.

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ACN
(Acetonitrile)
CAS [75-05-8]

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DMAc
(dimethylacetamide)
CAS [127-19-5]

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DMF
N,N-Dimethyl-formamide)
CAS [68-12-2]

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NMP
(N-Methyl-2-pyrrolidone)
CAS [872-50-4]

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Solvent Replacement

Achieving the right balance between performance and safety is critical in the area of chemical formulation. It can be a challenge to find solvents that are safe, yet powerful enough to dissolve difficult components and form stable formulations. As a dipolar aprotic solvent, DMSO is recognized as being a superior solvent and has been referred to as the “super solvent.” A defining characteristic of this powerful solvent which distinguishes it from other dipolar aprotic solvents is its safety and toxicology profile. In many cases, DMSO is less toxic than other solvents and is often used as the safe, yet effective alternative to more problematic solvents. While a superior solvent on its own, DMSO may need to be blended with other ingredients to mimic the solvency properties of other chemicals.

Gaylord’s mission is to assist formulators in replacing problematic solvents with comparable DMSO blends which are both safe and effective. 

Locate one of our Distributors or contact us to reach a member of our technical support team for assistance with your company’s reformulation efforts.

Our Products

Who We Are

Gaylord Chemical Company, LLC is the world’s preeminent producer of Dimethyl Sulfide, Dimethyl sulfoxide, and Procipient. Gaylord’s history dates back to 1962 when under the ownership of Crown Zellerbach, began an aggressive and comprehensive research program into the manufacture of Dimethyl Sulfide (DMS), Dimethyl Sulfoxide (DMSO) and other chemicals. The results of this extensive work would later give our company an astounding depth of knowledge about these products.

The assets of Crown Zellerbach were sold in 1986. In 1988 Gaylord Chemical Corporation was formed as a wholly-owned subsidiary. Ownership of the company transferred to Temple Inland Inc in 2002. Gaylord Chemical Company, LLC was formed as a result of a management buyout of Gaylord Chemical Corporation effective September 1, 2007.

Today, we continue to manufacture DMS and DMSO under the ownership of Eagle Tree Capital.

We pride ourselves in delivering quality products, technical support and world-class customer service. Gaylord Chemical is an on-purpose manufacturer of DMS and DMSO. We are focused on these products and the customers that use them.

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